WHO recommends two new drugs to treat patients with COVID-19
The World Health Organization (WHO) recommended on Thursday two new drugs to treat patients with COVID-19, one for patients with critical diseasea nd one for non-severe cases.
Severe or critical disease
The first drug, baricitinib, is a Janus kinase (JAK) inhibitor - a class of drugs used to treat autoimmune conditions, blood and bone marrow cancers, and rheumatoid arthritis.
According to the WHO Guideline Development Group, it is “strongly recommended” for patients with severe or critical disease in combination with corticosteroids.
The group of international experts based their recommendation on “moderate certainty evidence” that it improves survival and reduces the need for ventilation.
There was no observed increase in adverse effects.
The experts note that it has a similar effectas other arthritis drugs called interleukin-6 (IL-6) inhibitors. Because of that, when both drugs are available, they suggest choosing the best option based on cost, availability, and clinician exp ...
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